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na Administração Pública: Uma Análise Bibliométrica a Partir do Decreto Lei / An AnalysisBibliometric the Breaking of Decree Law 5,/ Decreto-Lei /98 – Estabelece normas, critérios e objectivos de qualidade com a finalidade de proteger o meio aquático e melhorar a. Decreto Nº Cargado por. Cristiano Amorim. Mapa Mental Resumo Licitacoes. Cargado por. Cristiano Amorim. Questões Decretos e

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Overexpressed galectin-3 in pancreatic cancer induces cell proliferation and invasion by binding Ras and activating Ras signaling. This abstract may be abridged. International journal of radiation oncology, biology, physics. Galectin-3 expression was measured by florescence intensity of each cell, representative cells correspond statistically to median fluorescence of all cells.

Galectin-3 and GLUT-1 presence, as evidenced by fluorescent immunostaining, was simultaneously increased in hypoxic CMT-U27 cells when compared with normoxic controls. When seeking an alignment with modern people management practices, the federal public administration assumes that there is an urgent need to modernize its practices.

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Among the outlined strategic objectives, those related to the People and Technology perspective can be directly associated with the Competency-based Management Model, adopted by the institution as one of its management strategies linked to the adequacy to the PNDP, focusing on the continuous development of the public servant.

The shared language attribute can also be highlighted, with the presence of specific vocabulary words and technical terms that facilitate communication in work groups, allowing for the development of common operative language, as argued by Retour and Krohmer However, remote access to EBSCO’s databases from non-subscribing institutions is not allowed if the purpose of the use is for commercial gain through cost reduction or avoidance for a non-subscribing institution.

GLUT-1, included as a well-known target lie hypoxic conditions, was also not increased in the presence of catalase.

British Journal of Educational Studies, 52 1 Siqueirahowever, argues that the development of new forms of management is based on a flexible organizational structure and a better adaptation to the external environment.


These results in a 507 model further point to an important hypoxia regulation of galectin-3, possibly associated to cancer aggressiveness. Hypoxyprobe-1 was included to confirm that this tissue was low in O 2 tension and CD31 staining further showed lack of significant neovascularization in the necrosis-surrounding areas Fig 6B.

The competency-based management model considers the participation of employees as a fundamental aspect to the implementation of the organizational strategy and the development of competitive advantage. Rio de Janeiro, RJ: For this, publications between the years to were analyzed in two research bases: In fact, the implementation of the model itself is a consequence of such articulation, which generated considerable gains for the university.

It should be noted that, when considering such a phenomenon, the competency-based management model could be enriched in its practical application, promoting real benefits for organizations, extrapolating the dimension of discourse and permeating the day-to-day of organizational operations, which would allow for the constitution of collective work.

All stained sections were examined under a light microscopy by three observers de Oliveira JT. Regulation of cancer-related gene expression by galectin-3 and the molecular mechanism of its nuclear import pathway.

In our series, spontaneous mammary carcinomas have shown some areas of hypoxia in specific locations suggesting that they may suffer different pressures of oxygen intermittent hypoxia. This ability to act collectively would be of a tacit nature and not possible to be replicated since the combination of factors would particularly belong to each collective body, to each organization Grimand, ; Michaux, The author emphasizes the complexity of the topic and states that decreti competency of a company or its sectors is not limited to the simple sum of the competencies of its members.

The mapping of work functions throughout STN was a fundamental input to the first competency-based performance assessment. The context of rapid changes in the current scenario, marked derceto the development of new technologies and frequent innovations, generates the need for organizations to respond with agility and efficiency. It is horizontal when the alignment of the people management subsystems is considered. Eighteen items were developed and grouped into six themes: Hypoxia-inducible factor-1 HIF-1 -independent microvascular angiogenesis in the aged rat brain.


Furthermore, strategies and practices in the field of public administration have been redirected to meet the complex demands of society. Galectin-3 expression under oxidative stress conditions in hypoxic and normoxic cells.

Hypoxia Up-Regulates Galectin-3 in Mammary Tumor Progression and Metastasis

Catalase treated CMT-U27 cells under normoxia presented galectin-3 in specific organelles; however in catalase-treated hypoxic cells galectin-3 localization was again mostly cytoplasmic.

Despite galectin-3 may be secreted to the extracellular space in an energy-independent manner [ 36 ], our present data seem not to support any additional differences in the secretion of the lectin at different points of hypoxia exposure S2 Fig. Michaux states that the concepts of individual, collective and organizational competency are related to different theoretical views, but that the combination of these concepts would allow for the discussion of the existence of a collective capacity within organizations that could help coordination, collective solution of problems, and integration of knowledge and practical knowledge that would be linked to collective performance.

Blue color shows the nucleus stained by DAPI. These results reinforce the difficulties faced by the Brazilian public administration due to the coexistence of the traditional bureaucratic model with premises defended by the managerial model of public administration.

Relative intensity of the indicated protein level bands normalizes to actin were measured. Our previous work regarding the differential expression of galectins-1 and -3 during the metastatic process in CMT pointed to the existence of hybrid but mainly galectinexpressing tumor cells in circulation which, after an initial homing period, gradually lose galectin-3 expression and gain that of galectin-1 [ 60 ].

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